pentobarbital will lower the level or influence of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will reduce the extent or influence of tamoxifen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.buprenorphine transdermal and pentobarbital each boost sedation. Stay